OICBB Seminar Series

Upcoming

The Ottawa Institute of Computational Biology and Bioinformatics announces its 2nd Computational Biology and Biomedical Informatics Student/Postdoc Poster Day. I hope many of you may remember the Computational Biology Poster Day last year, which was quite a success. As promised, we intend to make it an annual event. The date for the 2nd Poster Day is set for Thursday October 25th, 2012. The poster session will take place at the Atrium in the Roger Guindon Hall (RGN) at the U. Ottawa Faculty of Medicine between 9:30 am and 4:00 pm. We also reserved RGN 2005 auditorium for oral presentations and discussions.

This year event is again supported by our last year sponsors: The Fund for Interdisciplinary Initiatives from the U. Ottawa Office of the Vice-President Academic and Provost and Ottawa Institute of Systems Biology. The Fund for Interdisciplinary Initiatives approved very generous cash prizes to the Poster Day winners this year: $1000 for the best poster, $500 for the second and $250 for the third. Many thanks to our sponsors for their continuing support!

We are happy to have Prof. Igor Jurisica, Professor in Departments of Computer Science and Medical Biophysics, University of Toronto, Senior Scientist in Ontario Cancer Institute and Tier I Canada Research Chair in Integrative Cancer Informatics as our keynote speaker this year. The title of his lecture: “ Integrative cancer informatics. From biomarkers to new drugs and improved survival.”

A tentative schedule of the Poster Day follows:

9:30-10:45am - On site registration and posters set up;

10:45-12:00 - Opening remarks and Keynote Lecture;

12:00-1:00pm – Lunch catered on site;

12:00-3:30 – Poster presentation and discussion;

3:30-4:00 – Winners’ announcement and concluding remarks.

We invite all students and postdocs with relevant research interests to present their work. We would like to invite participants from all around Ottawa, including different departments in the U. Ottawa, OHRI, Carleton U., NRC, and Ottawa Hospitals. Anyone with relevant interests (either those who work in this research area or whose work is related to it) is welcome! Students and postdocs who wish to present their work should contact:

ILYA IOSHIKHES, Ph.D.
Associate Professor
Ottawa Institute of Computational Biology and Bioinformatics (OICBB)
Ottawa Institute of Systems Biology (OISB)
Department of Biochemistry, Microbiology and Immunology (BMI)
E-mail: iioschik@uottawa.ca

Past seminars

Dr. Quaid Morris
University of Toronto

"Predicting the targets of mRNA-binding proteins (and a bit of GeneMANIA)"

Tuesday November 23, 2010, 3:30pm - 4:30pm
Room 2003, AMP B
Roger Guindon Hall, University of Ottawa

Dr. Edward N. Trifonov
Head of Genome Diversity Center
Institute of Evolution
University of Haifa (Israel)

"Fundamental modules of protein structure and function"

Monday June 28, 2010, 3:30 p.m. - 4:30 p.m.
Room 3248 RGN

The protein sequences are highly non-uniform in terms of local sequence conservation. The map of the conserved motifs in a given protein appears as series of peaks, typically separated by 25-30 residues. The formatted protein sequence space made of all natural fragments of standard size consists of isolated large networks of pair-wise relatedness, such that fragments of a given network share both structure and function, while sequences are highly diverse. Each network, thus, represents a functionally and structurally specific protein module of rather standard size as above, originally dictated by polymer statistic properties of the proteins. The sequence networks projected on a protein sequence provide the map of modules of which the protein is built.

Dr. O. U. Sezerman
Head, Computational Biology Lab and Protein Engineering Lab
Sabanci University, Istanbul, Turkey

"Computational Methods for Protein Folding and Design Problem"

Thursday April 1, 2010, 1 p.m. - 2 p.m.
Room 1007 RGN

Determining the three dimensional structure of proteins starting from the sequence information only is one of the most challenging problems in bioinformatics. There are several experimental methods that are used to obtain the protein structure such as x-ray crystallography and NMR. All of these methods have their application limitations and they are not cost and labor effective. Therefore, there is an imminent need for computational methods to determine the protein structure and the rules governing the structure function relationship which will reveal clues about how the structure can be manipulated to create the desired impacts on the protein. This talk will focus on computational approaches we developed in our group to solve the protein structure determination problem and to understand the structure function relationship. All the applications will be on the use of these tools to enzyme engineering of lipases and cellulases.

Dr. Kenneth Edgecombe
Executive Director - HPCVL
High Performance Computing Virtual Laboratory – Kingston ON
(HPCVL is a joint enterprise of five Ontario Universities and three Colleges)

“Next Steps for High Performance Computer Data Centers: Medical and Life Sciences”

Wednesday February 3, 2010, 3:30 p.m. - 4:30 p.m.
Room 2003 AMP B, RGN